is >216 mg/dL (12mmol/L), then increase dose by .25-1.0U/injection AND/OR b. Glargine insulin cannot be diluted nor can detemir. Phase 1: Starting dose. Regardless of the insulin type, most cats require twice daily administration. Hence the ultra-long-acting human insulins, Glargine Lantus or Detemir Levemir, work best for these cats. Double-check the dose in the syringe. 3 Many veterinarians recommend Glargine ( Lantus, made by Sanofi Aventis ). insulin dose was not significantly different (P = 0.41). It is typically the recommended long acting insulin in the United Kingdom. Twelve client-owned dogs with diabetes mellitus were studied (8 females and 4 males). Lantus Insulin U-100 is used in the treatment of diabetes mellitus in multiple species including cats and dogs. Indications for increasing the dose of glargine insulin a. Glargine. Lessens signs of diabetes. When you eat carbs it raises BG as your body digests the food. Insulin glargine [GLAR geen], sold under the brand name Lantus among others, is a long-acting insulin, used in the management of type I and type II diabetes. Licensed for use in humans, a 10-ml vial of Lantus holds 1,000 units of the long-acting insulin. When insulin glargine is administered to diabetic dogs, it works by helping glucose enter the cells, so it can be turned into energy. Insulin Glargine. However, the most common causes for change are a reduction in food intake and an increase in exercise or activity. Glargine insulin, or Lantus, is an increasingly popular method for managing diabetes in felines.Diabetes mellitus, known commonly as type II or sugar diabetes, is a serious disease affecting a growing number of cats. Typically, for every 50 points above 150/8.3, the rule of thumb is 0.25u of insulin is needed..ECID - every cat is different. Lantus has proved very effective for diabetic cats and is available at most regular drugstores. Insulin is responsible for the proper usage of glucose by cells in the body. so you need insulin to lower your BG the same way that food raises BG. I often administer glargine before I have discussed the diagnosis and treatment plan with owners. In many cases, the starting dose of Lantus or Levemir has been 0.25 IU per kg of the cat's ideal weight and is always dosed BID (two times a day, 12 hours apart). Ketoacidotic cats may be treated with glargine s/c at the above dose rates in combination with regular insulin IM or IV (we have found IU regular insulin IM every 2-4 hours based on glucose conc works best). 1) Move the plunger up and down several times in the syringe - this will make it move more smoothly and help you draw the dose more easily. It is a long-acting insulin used in humans to provide a basis for glucose control which is then fine-tuned with short-acting insulins. 5, 21 - 23 The recommended starting dose is typically 0.25-0.50 U/kg every 12 hours (rounded down to the nearest unit, and generally ≤2 U/cat every 12 hours). An injectable drug, this medication works to regulate your diabetic cat's blood sugar. Do not dilute or mix with any other insulin or solution. Otherwise, you are likely to end up with the wrong dosage if you use a different type of syringe. However, the problem with buying Lantus in a 10ml vial is that, properly handled, Lantus (once opened) is usually only effective for 2-3 months and cats on a normally low dose of insulin don't use 1000 units of insulin in 3 months. Once a cat has been stabilised on glargine insulin (i.e. lantus is a background insulin, lasts about 24 hours. Adjusting glargine insulin dose. In cats, Caninsulin dosing is calculated on a per animal basis (initial dosing for cats is based on blood glucose results). As a result, diabetic cats have high levels of blood sugar. lantus just keeps you idling along. There is no true generic version of Lantus but there is a biosimilar drug that was released in 2016 called Basaglar. If the insulin dose is too high. glargine, PZI and demetir). Insulin for cats dosage. Use: To improve glycemic control in pediatric patients 6 years or older with type 1 diabetes mellitus. Common side effects include low blood sugar . Side Effects Since Novolin is intended to lower the blood sugar of the recipient, patients may experience hypoglycemia, or dangerously low blood sugar, if they take too large of a dose, which can be fatal. Figure 2 Standard deviation, as a metric of glycemic variability, of blood glucose curves (BGCs) performed for 8 consequent weeks in feline diabetic patients treated with insulin glargine 300 U/ml and low carbohydrate diet. The BG that indicates the dose of insulin is the nadir or lowest level. The generic name for Lantus is insulin glargine. This stubborn food-nibbling preference of cats is likely why we tend to have greater success with longer-acting insulin for putty tats (i.e. Indications for increasing the dose of glargine insulin; If pre-insulin glucose conc. One may need to adjust the amount and timing of short- or rapid-acting insulins and dosages of any oral anti-diabetic drugs See what others have said about Lantus (Insulin Glargine), including the effectiveness, ease of use and side effects. Caninsulin is mainly for dogs, though some cats do well on it. An overdose could seriously harm your cat. BG 150/8.3 or higher, and 3. after a week of therapy), the dose may need to be increased or decreased. The starting dose for insulin should not exceed 0.25-0.5 U/kg BID. Lantus has proved very effective for diabetic cats and is available at most regular drugstores. TESTED, TRUSTED, TAKEN. BG testing. A lot of the following is irrelevant at this point, because Lantus has become quite expensive. After dose and 22.3 reading, straight line drop to almost 12, now slight increase to 13.3. The remedy is a transparent and colorless solution for subcutaneous injection for blood sugar control in adults, adolescents, and children 6 years of age and older. For cats, the initial recommended dose of Vetsulin ® is 1 to 2 IU per injection. When your cat has a normal level of glucose in the blood the body works as it should and your cat will have fewer diabetic symptoms. The initial dose is 1 to 2 IU/cat twice a day. Good for them! Pdf Dose Accuracy And Injection Force Of Diffe Insulin. Instructions Recommended Dosage. In the cat, loss or dysfunction of beta cells is the result of insulin resistance, islet amyloidosis, or chronic lymphoplasmacytic pancreatitis.3 Studies have shown that diabetic cats have remission rates that have been reported to be variable (15-100%). Subjects received 30-minute intravenous infusions of insulin … "Hi Lydia, You should always go ahead and dose when you can - best to get the insulin into him when he needs it, and you never know what will happen that run - maybe he will push out longer! Both forms of distribution of the drug are in cardboard packaging. Steps to begin therapy. Dots (cats that achieved remission) and squares (cats that did not The probability of remission was greater for cats treated with glargine than cats treated with PZI or lente insulin. It can be difficult to regulate your diabetic cat's blood sugar levels, but glargine insulin may be more effective than other types of insulin because it lasts longer inside the cat's body. Your veterinarian has chosen this product to most closely match your pet's natural insulin. In cats, in which all blood glucose concentrations of a BGC range between 4.5 and 6.7 mmol/l and serum fructosamine is < 350 µmol/l, the insulin dose should be reduced in steps of 0.5 U/cat BID every 5-7 days. Used for over 25 years worldwide*. It is worth noting that due to species . Glargine-treated cats had lower mean 12h blood glucose concentrations on day 17 than PZI- or lente-treated cats, and all eight glargine-treated cats achieved remission compared to three PZI- and two lente-treated cats. In cats, initially administer twice-daily doses 12 . Lantus insulin for cats. This dose reduction will lower the likelihood of hypoglycemia [see Warnings and Precautions (5.3)]. Lantus (insulin glargine) is a long-acting type of insulin.Insulin helps to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2.Lantus is more popular than other insulins. ProZinc. 3 ml prefilled pens for single-use. These Highlights Do Not Include All The Information Needed To Use. This regime is continued until hydration restored and appetite reteurns, which usually occurs in 1-3 days. The correct dose is between 0.2 - 0.7 IU per kg of cat weight (0.1 - 0.3 IU per pound) administered after every about 12 hours using strictly a U-40 syringe and it should be done after meals. 1. The use of glargine for the control of diabetes in cats. Lantus Insulin controls blood glucose levels to help alleviate the symptoms of diabetes. Lantus Insulin requires a prescription from your veterinarian. When a dose of 0.5 U/cat SID is reached and blood glucose is still normal, insulin administration is ceased. Try to give this medication at about the same time each day. And Lantus is only one of the many diabetes medicines made by Sanofi. is > 12mmol/L, then increase dose by .25-1.0U/injection; AND/OR Insulin glargine, which is commonly used to treat people with diabetes mellitus, can also be used to treat diabetic cats. Adjusting glargine insulin dose Once a cat has been stabilized on glargine insulin (i.e. And if he doesn't and is high, you have the scale. Lantus Injection (Insulin Glargine) aids in the control of diabetes mellitus in cats. On "Lantus" and "Levemir", over 80% of my newly diagnosed diabetic cats recover within three months. It lasts 12 to 18 hours. Available in Solostar 3 ml prefilled pen and 10 ml vial. ProZinc Insulin U-40 for Dogs and Cats, 10-mL. Many veterinarians say it can last a cat owner for months given that a moderate dosage is 2 to 3 units twice daily. Lantus for cats. Diabetic remission is about good regulation early on rather than having a magic product. It is FDA approved, starts working quickly, and is long-lasting. 146872. To help learn which medicine may be right for you, select an option below. Most dogs suffer from Type 1 diabetes, while cats usually have Type 2 diabetes. If an individual dog does not achieve adequate regulation at dose, it can always be gradually increased. Glargine insulin cannot be mixed with other insulin because it would change the pH and the mechanism of absorption. Start the cat on 1 to 2 IU per injection given twice daily. Manufacturers now are leveraging the absolute necessity of insulin and raising prices drastically. Every day, millions of people count on once-daily Lantus to help lower their A1C. Vetsulin is an insulin designed to work specifically for your cat. Licensed for use in humans, a 10-ml vial of Lantus holds 1,000 units of the long-acting insulin. Lantus, Levemir and any insulins in a cartridge rather than a vial such as Caninsulin/Vetsulin pens. I remember someone on the old board who was giving as much as 30 units twice a day for an acromegaly cat :shock: The insulin you are using may not be working well for your cat. ProZinc insulin dose for cats. The twice-daily dosing of PROZINC ensures your cat receives an insulin that provides appropriate duration of action. [contradictory] It is used once a day as an injection just under the skin.Effects generally begin an hour after use. Glargine, rhPZI, porcine lente, and detemir insulin have all been demonstrated to achieve glycemic control in cats with twice-daily dosing. Further, every cat is different and some cats metabolize these insulins so quickly that they are not long-lasting at all and another insulin is a better choice. 2.4 Changing to LANTUS from Other Insulin Therapies • If changing patients from once-daily TOUJEO (insulin glargine) 300 Units/mL to once-daily LANTUS, the recommended initial LANTUS dose is 80% of the TOUJEO dose that is being discontinued. Diabetes Mellitus is a relatively common metabolic disease seen in middle aged cats and dogs. Patients with T2DM: Lantus ® dosing. "It's the insulin I reach for when there's a diabetic cat," Mihlfried said. It is used with U-100 insulin syringes only (sold separately). Lantus Insulin (insulin glargine injection) is an injectable, long-acting insulin for treating diabetes mellitus in dogs and cats. J Vet Intern Med. Lantus ® insulin (Glargine) was marketed for human diabetics as a "peakless" insulin, meaning that it maintains a glucoses in a narrow range. The dose is generally only a few units of insulin and the gradations on a syringe are tiny. FIG 2: Histograms indicate the number of blood glucose curves (%) from 12 dogs with naturally acquired diabetes mellitus treated by. I recall a day recently when it was as little as $100 - $110 a bottle. after a week of therapy), the dose may need to be increased or decreased. This dose reduction will lower the likelihood of hypoglycemia [see Warnings and Precautions (5.3)]. ONCE-DAILY LANTUS ® IS THE MOST PRESCRIBED 1 LONG-ACTING INSULIN. Should BG be tested just before or after injecting the insulin? While once-a-day dosing is adequate for humans, the duration of action in healthy cats is shorter and twice-daily dosing is recommended. Dogs and Cats. Insulin Injection Sites And Side Effects Dosage Lantus. Glargine is the only insulin that offers a chance of remission, meaning that your cat may . The feline dose of insulin is generally only a few units of insulin and the gradations on an insulin syringe are tiny. FREE shipping on this item. ProZinc Insulin U-40 for Dogs and Cats, 10-mL. Lantus ® insulin (Glargine) was marketed for human diabetics as a "peakless" insulin, meaning that it maintains a glucoses in a narrow range. Glargine (U-100 human recombinant; Lantus, Sanofi) is a longer-acting insulin commonly used by the Task Force in cats because it has an adequate duration of action in most diabetic cats. For cats, it is the same low-carbohydrate food as they receive as a meal, but hopefully the majority of food is given with the insulin. Researchers treated 10 diabetic dogs with an initial dose of 0.5 units glargine insulin per kilograms body weight injected under the skin twice daily.. Administer subcutaneously once daily at any time of day, but at the same time every day. Some of us prefer to split the Lantus dose, taking some in the morning and some in the evening to equal the complete dose.That way, only half is petering out after 20 hours, and the sugar levels stay more even throughout the day. There is currently no generic alternative for Lantus, but there is an alternative insulin with the same active ingredient as Lantus. Rx Glargine = Lantus: This acid pH insulin precipitates in the neutral pH of the body and is absorbed slowly. It comes in various forms and strengths with corresponding syringes for each strength. Lantus comes in 10 mL vials or 3 mL pens. It is a long-acting insulin used in humans to provide a basis for glucose control which is then fine-tuned with short-acting insulins. This dose reduction will lower the likelihood of hypoglycemia [see Warnings and Precautions (5.3)]. I purchase the box of "Levemir" and dispense the 3 ml vials to owners. 1. If changing patients from once-daily TOUJEO (insulin glargine) 300 units/mL to once-daily LANTUS, the recommended initial LANTUS dose is 80% of the TOUJEO dose that is being discontinued. If the cat received another kind of insulin previously, the starting dose should be raised or lowered by taking this information into account. Special Spotlight On Diabetes Insulins Toujeo Insulin Glargine. 62 Initial doses for detemir are similar to glargine, with 0.5 units/kg if blood glucose concentration is >360 mg/dL (20 mmol/L) and 0.25 units/kg if <360 mg/dL. $103.54 Autoship & Save. Lantus is a human insulin that works very well on cats. Lantus Insulin (insulin glargine injection) is an injectable, long-acting insulin for treating diabetes mellitus in dogs and cats. Results of the present study suggested that, in diabetic dogs fed a diet high in insoluble fiber, glargine insulin is a peakless insulin that does not induce a distinct blood glucose concentration nadir. Lantus insulin is a long-lasting, high-powered insulin used to help treat diabetes mellitus. One-year prospective randomized trial comparing efficacy of glargine and protamine zinc insulin in diabetic cats. Changing to LANTUS from Other Insulin Therapies. The objective of this study was to evaluate the safety and efficacy of insulin glargine in dogs with diabetes mellitus. This long-acting insulin is designed to be injected beneath . Cats should be started on twice-daily injections of Vetsulin at 12-hour intervals. It is used with U-100 insulin syringes only (sold separately). If pre-insulin glucose conc. Learn how Lantus helps cats and dogs with diabetes. administration of insulin glargine twice daily for 24 weeks . Lantus is a long-acting form of insulin formulated for injection underneath the skin. 4 Gostelow R, Scudder C, et al. He . However, it works effectively with the combination of a low-carb canned food diet (less than 7% carbohydrates). 12 . It is recommended you start Lantus at a dose of 0.3 units per kg of body weight, which should be administered twice daily. Like most forms of insulin, it was originally created to treat diabetes in people, but is being used more and more to help manage diabetes in cats and dogs. 2.4 Changing to LANTUS from Other Insulin Therapies • If changing patients from once-daily TOUJEO (insulin glargine) 300 Units/mL to once-daily LANTUS, the recommended initial LANTUS dose is 80% of the TOUJEO dose that is being discontinued. All dogs received insulin glargine every 12 hours for at least six months.The starting dose was 0.25-0.5 U/kg, SC, every 12 hours. Glargine insulin is a type of long-lasting insulin that has been approved by the FDA for use in humans. 1 ml of the drug contains 100 units of insulin. Multiple types of Insulin exist, so make sure you match the right type of syringe to your Insulin. Although most cats will require the same dose of insulin for long periods of time, it is possible for the cat's insulin requirements to change. The remaining 22 units would be given as a fast-acting insulin with each meal. FDA-approved for cats. 166. Experienced members on forum can help you determine the correct strategy for your cat when using depot insulin types. If that's not happening after 3 shots on an increase (a cycle is 3 shots), then an increase is in order. $108.99. PROZINC also uses specific syringes with calibrations suitable for cats (known as U-40) to deliver precise, accurate doses, reducing the risk of under- or overdosing. For glargine insulin, 0.3 U/kg (0.136 U/lb) SC twice daily is recommended as an initial dosage. 3 PROZINC ® (protamine zinc recombinant human insulin) cat product insert. -During clinical trials, patients receiving insulin glargine U-300 required 17.5% greater dose than patients treated with insulin glargine U-100. Lantus is a depot insulin and if you chop and change the dose it will mess up the depot and you may get wonky numbers. It is also used successfully to regulate blood sugar levels in diabetic cats. The dosage in both cats and dogs is 0.2 units/kg, but you should consult with your veterinarian before administering any injections. If they decide not to treat the cat, little has been lost as the syringes and insulin probably cost the clinic less than $1. phase. Lantus Insulin is an injectable medication used to control diabetic patients' blood sugar levels. 2.4 Changing to LANTUS from Other Insulin Therapies • If changing patients from once-daily TOUJEO (insulin glargine) 300 Units/mL to once-daily LANTUS, the recommended initial LANTUS dose is 80% of the TOUJEO dose that is being discontinued. Diabetes in cats refers to a condition where the pancreas cannot produce enough insulin or the cat's body becomes resistant to insulin. Lantus is a clear solution that is administered to patients by subcutaneous injection. This injectable medication helps regulate blood sugar in cats. 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